PINK1/Parkin-mediated mitophagy modulates cadmium-induced apoptosis in rat cerebral cortical neurons

PINK1/Parkin-mediated mitophagy modulates cadmium-induced apoptosis in rat cerebral cortical neurons

Cadmium is a persistent environmental pollutant whose neurotoxicity is of serious concern. Mitochondrial dysfunction and its mediated mitophagy and apoptosis are considered key events in Cd-induced neurological pathologies, but the exact molecular mechanism has not been fully elucidated. The aim of...

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Bibliographic Details
Main Authors: Shuangquan Wen, Li Wang, Chaofan Zhang, Ruilong Song, Hui Zou, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Zongping Liu, Yan Yuan
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Rat cerebral cortical neuron
PINK1/Parkin pathway
Mitophagy
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322008922

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http://www.sciencedirect.com/science/article/pii/S0147651322008922

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