The role of ER stress in lipid metabolism and lipotoxicity

The endoplasmic reticulum (ER) is a cellular organelle important for regulating calcium homeostasis, lipid metabolism, protein synthesis, and posttranslational modification and trafficking. Numerous environmental, physiological, and pathological insults disturb ER homeostasis, referred to as ER stre...

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Bibliographic Details
Main Authors: Jaeseok Han, Randal J. Kaufman
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752035207X