Widespread use of non-productive alternative splice sites in Saccharomyces cerevisiae.
Saccharomyces cerevisiae has been used as a model system to investigate the mechanisms of pre-mRNA splicing but only a few examples of alternative splice site usage have been described in this organism. Using RNA-Seq analysis of nonsense-mediated mRNA decay (NMD) mutant strains, we show that many S....
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3983031?pdf=render |