Investigating the Endo-Lysosomal System in Major Neurocognitive Disorders Due to Alzheimer’s Disease, Frontotemporal Lobar Degeneration and Lewy Body Disease: Evidence for SORL1 as a Cross-Disease Gene

Investigating the Endo-Lysosomal System in Major Neurocognitive Disorders Due to Alzheimer’s Disease, Frontotemporal Lobar Degeneration and Lewy Body Disease: Evidence for SORL1 as a Cross-Disease Gene

Dysfunctions in the endo-lysosomal system have been hypothesized to underlie neurodegeneration in major neurocognitive disorders due to Alzheimer’s disease (AD), Frontotemporal Lobar Degeneration (FTLD), and Lewy body disease (DLB). The aim of this study is to investigate whether these diseases shar...

Full description

Bibliographic Details
Main Authors: Luisa Benussi, Antonio Longobardi, Cemile Kocoglu, Matteo Carrara, Sonia Bellini, Clarissa Ferrari, Roland Nicsanu, Claudia Saraceno, Cristian Bonvicini, Silvia Fostinelli, Roberta Zanardini, Marcella Catania, Matthieu Moisse, Philip Van Damme, Giuseppe Di Fede, Giuliano Binetti, Christine Van Broeckhoven, Julie van der Zee, Roberta Ghidoni
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
SORL1
DNAJC6
PPT1
endo-lysosomal genes
NGS
cross-disease
Online Access:https://www.mdpi.com/1422-0067/22/24/13633

Internet

https://www.mdpi.com/1422-0067/22/24/13633

Similar Items