Role of a Real-Time TDM-Based Expert Clinical Pharmacological Advice Program in Optimizing the Early Pharmacokinetic/Pharmacodynamic Target Attainment of Continuous Infusion Beta-Lactams among Orthotopic Liver Transplant Recipients with Documented or Suspected Gram-Negative Infections

Role of a Real-Time TDM-Based Expert Clinical Pharmacological Advice Program in Optimizing the Early Pharmacokinetic/Pharmacodynamic Target Attainment of Continuous Infusion Beta-Lactams among Orthotopic Liver Transplant Recipients with Documented or Suspected Gram-Negative Infections

(1) Objectives: To describe the attainment of optimal pharmacokinetic/pharmacodynamic (PK/PD) targets in orthotopic liver transplant (OLT) recipients treated with continuous infusion (CI) beta-lactams optimized using a real-time therapeutic drug monitoring (TDM)-guided expert clinical pharmacologica...

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Bibliographic Details
Main Authors: Milo Gatti, Matteo Rinaldi, Cristiana Laici, Antonio Siniscalchi, Pierluigi Viale, Federico Pea
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Antibiotics
Subjects:
orthotopic liver transplant recipients
beta-lactams
continuous infusion
intensive care unit
Gram-negative infections
PK/PD target attainment
Online Access:https://www.mdpi.com/2079-6382/12/11/1599

Internet

https://www.mdpi.com/2079-6382/12/11/1599

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