The Inducible microRNA-21 Negatively Modulates the Inflammatory Response in Teleost Fish via Targeting IRAK4

The Inducible microRNA-21 Negatively Modulates the Inflammatory Response in Teleost Fish via Targeting IRAK4

Eradication of bacterial infection requires timely and appropriate immune and inflammatory responses, but excessive induction of inflammatory cytokines can cause acute or chronic inflammatory disorders. Thus, various layers of negative regulators and mechanisms are needed to ensure maintenance of th...

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Bibliographic Details
Main Authors: Qing Chu, Xiaolong Yan, Lihua Liu, Tianjun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
miR-21
inflammation
IRAK4
NF-κB signaling
fish
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01623/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01623/full

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