Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN‐003 (VOICE) study

Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN‐003 (VOICE) study

Introduction In the Microbicide Trial Network MTN‐003 (VOICE) study, a Phase IIB pre‐exposure prophylaxis trial of daily oral or vaginal tenofovir (TFV), product adherence was poor based on pharmacokinetic (PK) drug detection in a random subsample. Here, we sought to compare behavioural and PK measu...

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Bibliografski detalji
Glavni autori: Ariane van derStraten, Elizabeth R Brown, Jeanne M Marrazzo, Michael Z Chirenje, Karen Liu, Kailazarid Gomez, Mark A Marzinke, Jeanna M Piper, Craig W Hendrix, on behalf of the MTN‐003 VOICE Protocol Team for the Microbicide Trials Network
Format: Članak
Jezik:English
Izdano: Wiley 2016-01-01
Serija:Journal of the International AIDS Society
Teme:
microbicide
pre‐exposure prophylaxis
adherence measurement
pharmacokinetic drug detection
HIV
Online pristup:https://doi.org/10.7448/IAS.19.1.20642

Internet

https://doi.org/10.7448/IAS.19.1.20642

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