A thiol probe for measuring unfolded protein load and proteostasis in cells
Proteostasis is maintained through a number of molecular mechanisms, some of which function to protect the folded state of proteins. Here the authors demonstrate the use of TPE-MI in a fluorigenic dye assay for the quantitation of unfolded proteins that can be used to assess proteostasis on a cellul...
প্রধান লেখক: | , , , , , , , , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Nature Portfolio
2017-09-01
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মালা: | Nature Communications |
অনলাইন ব্যবহার করুন: | https://doi.org/10.1038/s41467-017-00203-5 |