Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility

Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility

Abstract Background Zebrafish can faithfully regenerate injured fins through the formation of a blastema, a mass of proliferative cells that can grow and develop into the lost body part. After amputation, various cell types contribute to blastema formation, where each cell type retains fate restrict...

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Bibliographic Details
Main Authors: Hyung Joo Lee, Yiran Hou, Yujie Chen, Zea Z. Dailey, Aiyana Riddihough, Hyo Sik Jang, Ting Wang, Stephen L. Johnson
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Biology
Subjects:
Regeneration
DNA methylation
Fate restriction
Zebrafish
Fin
Osteoblast
Online Access:http://link.springer.com/article/10.1186/s13059-020-1948-0

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http://link.springer.com/article/10.1186/s13059-020-1948-0

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