Cathepsin L Helps to Defend Mice from Infection with Influenza A.

Host-derived proteases can augment or help to clear infections. This dichotomy is exemplified by cathepsin L (CTSL), which helps Hendra virus and SARS coronavirus to invade cells, but is essential for survival in mice with mycoplasma pneumonia. The present study tested the hypothesis that CTSL prote...

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Bibliographic Details
Main Authors: Xiang Xu, John R Greenland, Jeffrey E Gotts, Michael A Matthay, George H Caughey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5055332?pdf=render