Genetic evidence for causal effects of leukocyte counts on risk for rheumatoid arthritis

Abstract Rheumatoid arthritis (RA) is an autoimmune disease characterized by the accumulation of leukocytes and inflammatory mediators within the synovial tissue. Leukocyte counts are proposed to play a role in the pathogenesis of RA. However, the causality remains unclear. To investigate the causal...

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Bibliographic Details
Main Authors: Jin-Mei You, Yao-Chen Zhang, Ke-Yi Fan, Shang-Kai Bai, Zi-Yu Zhang, He-Yi Zhang, Ting Cheng, Yue-Hong Huo, Cai-Hong Wang, Xiao-Feng Li, Sheng-Xiao Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46888-1