Cdk6: At the interface of Rb and p53

In cancer the activity of cyclin-dependent kinase 4-(CDK4) and cyclin-dependent kinase 6 (CDK6)-cyclin complexes are frequently altered with enhanced CDK6 expression found in hematopoietic malignancies. Our latest findings show a so far unknown role of Cdk6 during oncogene-induced stress and transfo...

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Bibliographic Details
Main Authors: Sofie Nebenfuehr, Florian Bellutti, Veronika Sexl
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2018.1511206