Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders

Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders

The dihydropyrimidinase-like (DPYSL) proteins, also designated as the collapsin response mediators (CRMP) proteins, constitute a family of five cytosolic phosphoproteins abundantly expressed in the developing nervous system but down-regulated in the adult mouse brain. The DPYSL proteins were initial...

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Bibliographic Details
Main Authors: Florence Desprez, Dévina C. Ung, Patrick Vourc’h, Médéric Jeanne, Frédéric Laumonnier
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neuroscience
Subjects:
dihydropyrimidinase-like proteins
collapsin response mediator proteins
neurodevelopmental disorders (NDDs)
human genetics research
neuronal development
synaptic physiopathology
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1154446/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.1154446/full

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