Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer

Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer

Tongue squamous cell carcinoma is an aggressive oral cancer with a high incidence of metastasis and poor prognosis. Most of the oral cavity cancer patients present in clinics with locally advanced unresectable tumors. Neoadjuvant treatment is beneficial for these individuals as it reduces the tumor...

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Bibliographic Details
Main Authors: Irene A. George, Gajanan Sathe, Vivek Ghose, Anuradha Chougule, Pratik Chandrani, Vijay Patil, Vanita Noronha, R. Venkataramanan, Sewanti Limaye, Akhilesh Pandey, Kumar Prabhash, Prashant Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tongue cancer
proteome
phosphoproteome
neoadjuvant chemotherapy resistance
rho GTPases signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.957983/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.957983/full

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