Lipid emulsion mitigates intravenous amiodarone toxicity in a rat model

AbstractIntroduction Our study investigated whether lipid emulsion therapy could act as an antidote for intravenous amiodarone toxicity in a rat model.Methods 20 rats were randomised to receive lipid emulsion (ILE) or saline. Rats were infused with amiodarone at 1 mg/kg/min for 20 min. ILE rats then...

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Bibliographic Details
Main Authors: Rachael Stewart, Verity Newman, Martyn Harvey, Mingtan Tang, Zimei Wu, Grant Cave
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Toxicology Communications
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/24734306.2022.2031565