Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice.

Mucosal tolerance to E-selectin prevents stroke and protects against ischemic brain damage in experimental models of stroke studying healthy animals or spontaneously hypertensive stroke-prone rats. A reduction in inflammation and neural damage was associated with immunomodulatory or "tolerogeni...

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Bibliographic Details
Main Authors: Xinhui Li, Kory R Johnson, Mark Bryant, Abdel G Elkahloun, Marcelo Amar, Alan T Remaley, Ranil De Silva, John M Hallenbeck, Jacqueline A Quandt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3119064?pdf=render