Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis
Abstract. Background:. Liver cancer is largely resistant to chemotherapy. This study aimed to identify the effective chemotherapeutics for β-catenin-activated liver cancer which is caused by gain-of-function mutation of catenin beta 1 (CTNNB1), the most frequently altered proto-oncogene in hepatic...
| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Wolters Kluwer
2024-01-01
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| シリーズ: | Chinese Medical Journal |
| オンライン･アクセス: | http://journals.lww.com/10.1097/CM9.0000000000002816 |