Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study

Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study

Abstract Background Congenital human cytomegalovirus (cCMV) infection can cause sensorineural hearing loss and neurodevelopmental disabilities in children. Ganciclovir and valganciclovir (GCV/VGCV) improve long-term audiologic and neurodevelopmental outcomes for patients with cCMV infection; however...

Full description

Bibliographic Details
Main Authors: Yuka Torii, Kazuhiro Horiba, Jun-ichi Kawada, Kazunori Haruta, Makoto Yamaguchi, Takako Suzuki, Hideko Uryu, Naoyuki Kashiwa, Keiji Goishi, Tomoo Ogi, Yoshinori Ito
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Infectious Diseases
Subjects:
Cytomegalovirus
Ganciclovir
Valganciclovir
Congenital cytomegalovirus infection
Drug resistance
Long-read sequencing
Online Access:https://doi.org/10.1186/s12879-022-07537-6

Internet

https://doi.org/10.1186/s12879-022-07537-6

Similar Items