Three-dimensional culture model to study the biology of vacuolated notochordal cells from mouse nucleus pulposus explants

Three-dimensional culture model to study the biology of vacuolated notochordal cells from mouse nucleus pulposus explants

Intervertebral disc degeneration (IDD) involves cellular changes in the nucleus pulposus (NP) characterised by a decline of the large vacuolated notochordal cells (vNCs) and a rise of smaller vacuole-free mature chondrocyte-like NP cells. An increasing number of studies demonstrate that notochordal...

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Bibliographic Details
Main Authors: L Paillat, K Coutant, M Dutilleul, S Le Lay, A Camus
Format: Article
Language:English
Published: AO Research Institute Davos 2023-03-01
Series:European Cells & Materials
Subjects:
intervertebral disc
nucleus pulposus cells
vacuolated notochordal cell
ex vivo mouse tissue
three-dimensional culture system
hypoxia
tissue engineering.
Online Access:https://www.ecmjournal.org/papers/vol045/pdf/v045a06.pdf

Internet

https://www.ecmjournal.org/papers/vol045/pdf/v045a06.pdf

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