Higher docosahexaenoic acid levels lower the protective impact of eicosapentaenoic acid on long-term major cardiovascular events

IntroductionLong-chain omega-3 polyunsaturated fatty acids (OM3 PUFA) are commonly used for cardiovascular disease prevention. High-dose eicosapentaenoic acid (EPA) is reported to reduce major adverse cardiovascular events (MACE); however, a combined EPA and docosahexaenoic acid (DHA) supplementatio...

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Bibliographic Details
Main Authors: Viet T. Le, Stacey Knight, Jeramie D. Watrous, Mahan Najhawan, Khoi Dao, Raymond O. McCubrey, Tami L. Bair, Benjamin D. Horne, Heidi T. May, Joseph B. Muhlestein, John R. Nelson, John F. Carlquist, Kirk U. Knowlton, Mohit Jain, Jeffrey L. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1229130/full