The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

Adiponectin-mediated pathways contribute to mammalian homeostasis; however, little is known about adiponectin and adiponectin receptor signaling in arthropods. In this study, we demonstrate that Ixodes scapularis ticks have an adiponectin receptor-like protein (ISARL) but lack adiponectin, suggestin...

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Bibliographic Details
Main Authors: Xiaotian Tang, Yongguo Cao, Gunjan Arora, Jesse Hwang, Andaleeb Sajid, Courtney L Brown, Sameet Mehta, Alejandro Marín-López, Yu-Min Chuang, Ming-Jie Wu, Hongwei Ma, Utpal Pal, Sukanya Narasimhan, Erol Fikrig
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
adiponectin receptor
Ixodes scapularis
Borrelia burgdorferi
Online Access:https://elifesciences.org/articles/72568

Internet

https://elifesciences.org/articles/72568

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