Alterations in the white matter structure of major depressive disorder patients and their link to childhood trauma

Alterations in the white matter structure of major depressive disorder patients and their link to childhood trauma

ObjectivesMajor Depressive Disorder (MDD) is significantly influenced by childhood trauma (CT), affecting brain anatomy and functionality. Despite the unique disease trajectory in MDD patients with CT, the underlying neurobiological mechanisms remain unclear. Our objective is to investigate CT’s imp...

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Bibliographic Details
Main Authors: Haomian Zhao, Bei Rong, Guoqing Gao, Mingzhe Zhou, Junhua Huang, Ning Tu, Lihong Bu, Ling Xiao, Gaohua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
childhood trauma
diffusion tensor imaging(DTI)
fractional anisotropy
tract-based spatial statistics(TBSS)
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1364786/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1364786/full

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