Impact of IFN-γ Deficiency on the Cardiomyocyte Function in the First Stage of Experimental Chagas Disease

Impact of IFN-γ Deficiency on the Cardiomyocyte Function in the First Stage of Experimental Chagas Disease

Chagas disease (CD) is caused by the parasitic protozoan <i>T. cruzi.</i> The progression of CD in ~30% of patients results in Chagasic Cardiomyopathy (CCM). Currently, it is known that the inflammatory system plays a significant role in the CCM. Interferon-gamma (IFN-γ) is the major cyt...

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Bibliographic Details
Main Authors: Danilo Roman-Campos, Policarpo Sales-Junior, Alexandre D. Costa, Diego Santos Souza, Artur Santos-Miranda, Julliane V. Joviano-Santos, Catherine Ropert, Jader S. Cruz
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
Chagas disease
cardiomyocytes
L-type calcium current
interferon gamma
Online Access:https://www.mdpi.com/2076-2607/10/2/271

Internet

https://www.mdpi.com/2076-2607/10/2/271

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