Dimerization of the type IV pilin from Pseudomonas aeruginosa strain K122-4 results in increased helix stability as measured by time-resolved hydrogen-deuterium exchange

Truncated pilin monomers from Pseudomonas aeruginosa strain K122-4 (ΔK122) have been shown to enter a monomer-dimer equilibrium in solution prior to oligomerization into protein nanotubes. Here, we examine the structural changes occurring between the monomeric and dimeric states of ΔK122 using time-...

Full description

Bibliographic Details
Main Authors: Cristina Lento, Derek J. Wilson, Gerald F. Audette
Format: Article
Language:English
Published: AIP Publishing LLC and ACA 2016-01-01
Series:Structural Dynamics
Online Access:http://dx.doi.org/10.1063/1.4929597