Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome

Rare single‐nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome

Abstract Background Approximately 5% of colorectal cancers (CRCs) are hereditary. Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is the most common form of recognized hereditary CRC. Although Iran, as a developing country, has a high incidence of CRC, the spect...

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Bibliographic Details
Main Authors: Seyed Mohsen Mirabdolhosseini, Mohammad Yaghoob Taleghani, Leili Rejali, Hossein Sadeghi, Nayeralsadat Fatemi, Mehdi Tavallaei, Amin Famil Meyari, Narges Saeidi, Pardis Ketabi Moghadam, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Ehsan Nazemalhosseini Mojarad
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cancer Reports
Subjects:
non‐pathogenic variants
Lynch syndrome
MLH1
MSH2
pathogenic variants
Online Access:https://doi.org/10.1002/cnr2.1930

Internet

https://doi.org/10.1002/cnr2.1930

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