Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

<p>Abstract</p> <p>Background</p> <p>There are no proven therapies that modify the structural changes associated with osteoarthritis (OA). Preclinical data suggests that intra-articular recombinant human BMP-7 (bone morphogenetic protein-7) has reparative effects on car...

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Bibliographic Details
Main Authors: Kissin Eugene, Jonas Beth L, Pike Marilyn C, Hunter David J, Krop Julie, McAlindon Tim
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/232