Saffron Extract Attenuates Anxiogenic Effect and Improves Cognitive Behavior in an Adult Zebrafish Model of Traumatic Brain Injury

Saffron Extract Attenuates Anxiogenic Effect and Improves Cognitive Behavior in an Adult Zebrafish Model of Traumatic Brain Injury

Traumatic brain injury (TBI) has the highest mortality rates worldwide, yet effective treatment remains unavailable. TBI causes inflammatory responses, endoplasmic reticulum stress, disruption of the blood–brain barrier and neurodegeneration that lead to loss of cognition, memory and motor skills. S...

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Bibliographic Details
Main Authors: Victoria Chaoul, Maria Awad, Frederic Harb, Fadia Najjar, Aline Hamade, Rita Nabout, Jihane Soueid
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
traumatic brain injury
saffron
zebrafish
anxiolytic
fear disinhibition
memory performance
Online Access:https://www.mdpi.com/1422-0067/23/19/11600

Internet

https://www.mdpi.com/1422-0067/23/19/11600

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