Stable Frequencies of HLA-C*03:04/Peptide-Binding KIR2DL2/3+ Natural Killer Cells Following Vaccination

Stable Frequencies of HLA-C*03:04/Peptide-Binding KIR2DL2/3+ Natural Killer Cells Following Vaccination

Inhibitory KIRs play a central role in regulating NK cell activity. KIR2DL2/3 bind to HLA-C molecules, but the modulation of these interactions by viral infections and presentation of viral epitopes is not well-understood. We investigated whether the frequencies of KIR2DL2/3+ NK cells recognizing HL...

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Bibliographic Details
Main Authors: Maja Christiane Ziegler, Ferran Borràs Grañana, Wilfredo F. Garcia-Beltran, Julian Schulze zur Wiesch, Christian Hoffmann, Anne Rechtien, Sebastian Lunemann, Marcus Altfeld
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
HLA
KIR
NK cells
HCV
HIV
YFV vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02361/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02361/full

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