A Mixed Thermosensitive Hydrogel System for Sustained Delivery of Tacrolimus for Immunosuppressive Therapy

A Mixed Thermosensitive Hydrogel System for Sustained Delivery of Tacrolimus for Immunosuppressive Therapy

Tacrolimus is an immunosuppressive agent for acute rejection after allotransplantation. However, the low aqueous solubility of tacrolimus poses difficulties in formulating an injection dosage. Polypeptide thermosensitive hydrogels can maintain a sustained release depot to deliver tacrolimus. The cop...

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Bibliographic Details
Main Authors: Hsiu-Chao Lin, Madonna Rica Anggelia, Chih-Chi Cheng, Kuan-Lin Ku, Hui-Yun Cheng, Chih-Jen Wen, Aline Yen Ling Wang, Cheng-Hung Lin, I-Ming Chu
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Pharmaceutics
Subjects:
allotransplantation
hydrogels
sustained delivery
tacrolimus
Online Access:https://www.mdpi.com/1999-4923/11/8/413

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https://www.mdpi.com/1999-4923/11/8/413

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