The association of dietary phytochemical index and nonalcoholic fatty liver disease
Abstract Consumption of phytochemical‐rich foods relates to the prevention of chronic diseases. In this study we assessed the dietary phytochemical index (PI) in metabolic parameters, liver enzymes, and severity of fibrosis among nonalcoholic fatty liver disease patients. This cross‐sectional study...
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| Format: | Article |
| Language: | English |
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Wiley
2023-07-01
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| Series: | Food Science & Nutrition |
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| Online Access: | https://doi.org/10.1002/fsn3.3389 |
| _version_ | 1797780623102836736 |
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| author | Bijan Ahmadi Amirhossein Ramezani Ahmadi Mohamadreza Jafari Nava Morshedzadeh |
| author_facet | Bijan Ahmadi Amirhossein Ramezani Ahmadi Mohamadreza Jafari Nava Morshedzadeh |
| author_sort | Bijan Ahmadi |
| collection | DOAJ |
| description | Abstract Consumption of phytochemical‐rich foods relates to the prevention of chronic diseases. In this study we assessed the dietary phytochemical index (PI) in metabolic parameters, liver enzymes, and severity of fibrosis among nonalcoholic fatty liver disease patients. This cross‐sectional study was conducted on 210 patients with NAFLD. Fibrosis‐4 index (FLB4), nonalcoholic fatty liver disease fibrosis score (NFS), FBS, lipids profile, AST, ALT, ALP, and GGT were measured. PI was calculated through the information obtained from a validated semi‐quantitative food frequency. Multiple regression models were used to estimate mean difference changes in the evaluated variables associated with various dietary PI. Participants' mean ± SD of age and BMI were 39.23 ± 10.52 and 24.40 ± 2.64, respectively. We found that DPI is inversely associated with serum TG, TC, and LDL‐C and directly associated with serum HDL‐C and a higher score in DPI is associated with lower scores in NFS and FIB‐4. Multivariate linear regression showed that there is an inverse association between DPI and AST, ALT, ALP, GGT, NFS, and FIB‐4. Higher dietary PI could impact on reduction of NAFLD progression and improvement of metabolic parameters. |
| first_indexed | 2024-03-12T23:46:41Z |
| format | Article |
| id | doaj.art-a462df95070742e8878742ef83742690 |
| institution | Directory Open Access Journal |
| issn | 2048-7177 |
| language | English |
| last_indexed | 2024-03-12T23:46:41Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Science & Nutrition |
| spelling | doaj.art-a462df95070742e8878742ef837426902023-07-14T06:57:56ZengWileyFood Science & Nutrition2048-71772023-07-011174010401910.1002/fsn3.3389The association of dietary phytochemical index and nonalcoholic fatty liver diseaseBijan Ahmadi0Amirhossein Ramezani Ahmadi1Mohamadreza Jafari2Nava Morshedzadeh3Gastroenterology and Hepatology Research Center Kerman University of Medical Sciences Kerman IranIsfahan Endocrine and Metabolism Research Center Isfahan University of Medical Sciences Isfahan IranDepartment of Nutrition, Faculty of Public Health Kerman University of Medical Sciences Kerman IranGastroenterology and Hepatology Research Center Kerman University of Medical Sciences Kerman IranAbstract Consumption of phytochemical‐rich foods relates to the prevention of chronic diseases. In this study we assessed the dietary phytochemical index (PI) in metabolic parameters, liver enzymes, and severity of fibrosis among nonalcoholic fatty liver disease patients. This cross‐sectional study was conducted on 210 patients with NAFLD. Fibrosis‐4 index (FLB4), nonalcoholic fatty liver disease fibrosis score (NFS), FBS, lipids profile, AST, ALT, ALP, and GGT were measured. PI was calculated through the information obtained from a validated semi‐quantitative food frequency. Multiple regression models were used to estimate mean difference changes in the evaluated variables associated with various dietary PI. Participants' mean ± SD of age and BMI were 39.23 ± 10.52 and 24.40 ± 2.64, respectively. We found that DPI is inversely associated with serum TG, TC, and LDL‐C and directly associated with serum HDL‐C and a higher score in DPI is associated with lower scores in NFS and FIB‐4. Multivariate linear regression showed that there is an inverse association between DPI and AST, ALT, ALP, GGT, NFS, and FIB‐4. Higher dietary PI could impact on reduction of NAFLD progression and improvement of metabolic parameters.https://doi.org/10.1002/fsn3.3389dietary phytochemical indexliver enzymesmetabolic parametersnonalcoholic fatty liver disease |
| spellingShingle | Bijan Ahmadi Amirhossein Ramezani Ahmadi Mohamadreza Jafari Nava Morshedzadeh The association of dietary phytochemical index and nonalcoholic fatty liver disease Food Science & Nutrition dietary phytochemical index liver enzymes metabolic parameters nonalcoholic fatty liver disease |
| title | The association of dietary phytochemical index and nonalcoholic fatty liver disease |
| title_full | The association of dietary phytochemical index and nonalcoholic fatty liver disease |
| title_fullStr | The association of dietary phytochemical index and nonalcoholic fatty liver disease |
| title_full_unstemmed | The association of dietary phytochemical index and nonalcoholic fatty liver disease |
| title_short | The association of dietary phytochemical index and nonalcoholic fatty liver disease |
| title_sort | association of dietary phytochemical index and nonalcoholic fatty liver disease |
| topic | dietary phytochemical index liver enzymes metabolic parameters nonalcoholic fatty liver disease |
| url | https://doi.org/10.1002/fsn3.3389 |
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