Comparison of LC-MS<sup>3</sup> and LC-MRM Methods for Quantifying Amantadine and Its Application in Therapeutic Amantadine Monitoring in Human Plasma

A simple sample preprocessing method was developed for the quantitative determination of amantadine (AMT) in human plasma by liquid chromatography-tandem mass spectrometry cubed (LC-MS<sup>3</sup>). The LC-MS<sup>3</sup> system comprised a Shimadzu Exion LC-20AD HPLC pump cou...

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Bibliographic Details
Main Authors: Qiang Sun, Haiwei Cao, Yong Liu, Yanyan Li, Jing Huang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/21/7619