Developing sero-diagnostic tests to facilitate Plasmodium vivax Serological Test-and-Treat approaches: modeling the balance between public health impact and overtreatment

Developing sero-diagnostic tests to facilitate Plasmodium vivax Serological Test-and-Treat approaches: modeling the balance between public health impact and overtreatment

Abstract Background Eliminating Plasmodium vivax will require targeting the hidden liver-stage reservoir of hypnozoites. This necessitates new interventions balancing the benefit of reducing vivax transmission against the risk of over-treating some individuals with drugs which may induce haemolysis....

Full description

Bibliographic Details
Main Authors: Thomas Obadia, Narimane Nekkab, Leanne J. Robinson, Chris Drakeley, Ivo Mueller, Michael T. White
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Medicine
Subjects:
Plasmodium vivax malaria
Test development
Serological test-and-treat
Modeling
Public health interventions
Overtreatment
Online Access:https://doi.org/10.1186/s12916-022-02285-5

Internet

https://doi.org/10.1186/s12916-022-02285-5

Similar Items