Design, synthesis and biological activity of novel chalcone derivatives containing indole

In this study, 24 chalcone derivatives containing indole were designed and synthesized. Some of the target compounds exhibited significant antiviral and antibacterial effects. The results of EC50 test against tobacco mosaic virus showed that the EC50 value of curative activity of D11 was 107.4 μg/mL...

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Bibliographic Details
Main Authors: Die Hu, Nian Zhang, Yuanquan Zhang, Chunmei Yuan, Chenyu Gong, Yuanxiang Zhou, Wei Xue
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223002381