FTIR spectroscopy as a unified method for simultaneous analysis of intra- and extracellular metabolites in high-throughput screening of microbial bioprocesses

FTIR spectroscopy as a unified method for simultaneous analysis of intra- and extracellular metabolites in high-throughput screening of microbial bioprocesses

Abstract Background Analyses of substrate and metabolites are often bottleneck activities in high-throughput screening of microbial bioprocesses. We have assessed Fourier transform infrared spectroscopy (FTIR), in combination with high throughput micro-bioreactors and multivariate statistical analys...

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Bibliographic Details
Main Authors: Gergely Kosa, Volha Shapaval, Achim Kohler, Boris Zimmermann
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Microbial Cell Factories
Subjects:
Microcultivation
Oleaginous fungi
Citric acid
High-throughput screening
Fourier transform infrared spectroscopy
Partial least squares regression
Online Access:http://link.springer.com/article/10.1186/s12934-017-0817-3

Internet

http://link.springer.com/article/10.1186/s12934-017-0817-3

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