Functional analysis of the Candida albicans kinome reveals Hrr25 as a regulator of antifungal susceptibility

Summary: Candida albicans is a leading cause of death due to systemic fungal infections. Poor patient outcomes are attributable to the limited number of antifungal classes and the increasing prevalence of drug resistance. Protein kinases have emerged as rewarding targets in the development of drugs...

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Bibliographic Details
Main Authors: Yunjin Lee, Sean D. Liston, Dongyeob Lee, Nicole Robbins, Leah E. Cowen
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007039