Chk1 haploinsufficiency results in anemia and defective erythropoiesis.
Erythropoiesis is a highly regulated and well-characterized developmental process responsible for providing the oxygen transport system of the body. However, few of the mechanisms involved in this process have been elucidated. Checkpoint Kinase 1 (Chk1) is best known for its role in the cell cycle a...
Main Authors: | Nathan C Boles, Sirisha Peddibhotla, Alice J Chen, Margaret A Goodell, Jeffrey M Rosen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2798715?pdf=render |
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