Formation and Characterisation of Posaconazole Hydrate Form

Posaconazole is an API added as Form I for the production of oral suspensions, but it is found as Form-S in the final formulation. In this study, it was found that this polymorphic conversion, which may affect the bioavailability, is due to an interaction with water. However, the relatively poor wet...

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Bibliographic Details
Main Authors: Michail Lykouras, Malvina Orkoula, Christos Kontoyannis
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/1/65