Comparative study of Wuhan-like and omicron-like variants of SARS-CoV-2 in experimental animal models

Comparative study of Wuhan-like and omicron-like variants of SARS-CoV-2 in experimental animal models

Introduction. The variability of SARS-CoV-2 appeared to be higher than expected, the emergence of new variants raises concerns. The aim of the work was to compare the pathogenicity of the Wuhan and BA.1.1/Omicron variants in BALB/c mice and Syrian hamsters. Materials and methods. The study use...

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Main Authors: Irina A. Leneva, Daria I. Smirnova, Nadezhda P. Kartashova, Anastasiia V. Gracheva, Anna V. Ivanina, Ekaterina A. Glubokova, Ekaterina R. Korchevaya, Andrey A. Pancratov, Galina V. Trunova, Varvara A. Khokhlova, Oksana A. Svitich, Vitaly V. Zverev, Evgeny B. Faizuloev
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2022-11-01
Series:Вопросы вирусологии
Subjects:
sars-cov-2 variants
balb/c mice
transgenic b6.cg-tg(k18-ace2)2prlmn/hemi hemizygous for tg(k18-ace2)2prlmn mice
syrian golden hamsters
sars-cov-2 animal models
Online Access:https://virusjour.crie.ru/jour/article/viewFile/627/416

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https://virusjour.crie.ru/jour/article/viewFile/627/416

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