Longitudinal monitoring of amyotrophic lateral sclerosis by diffusion tensor imaging: Power calculations for group studies

Longitudinal monitoring of amyotrophic lateral sclerosis by diffusion tensor imaging: Power calculations for group studies

IntroductionDiffusion tensor imaging (DTI) can be used to map disease progression in amyotrophic lateral sclerosis (ALS) and therefore is a promising candidate for a biomarker in ALS. To this end, longitudinal study protocols need to be optimized and validated regarding group sizes and time interval...

Full description

Bibliographic Details
Main Authors: Anna Behler, Dorothée Lulé, Albert C. Ludolph, Jan Kassubek, Hans-Peter Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Neuroscience
Subjects:
Amyotrophic Lateral Sclerosis
Diffusion Tensor Imaging
longitudinal design
statistical power
study optimization
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.929151/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.929151/full

Similar Items