Clonal hematopoiesis impacts frailty in newly diagnosed multiple myeloma patients: a retrospective multicenter analysis

Clonal hematopoiesis impacts frailty in newly diagnosed multiple myeloma patients: a retrospective multicenter analysis

Abstract Somatic mutations of hematopoietic cells in the peripheral blood of normal individuals refer to clonal hematopoiesis of indeterminate potential (CHIP), which is associated with a 0.5–1% risk of progression to hematological malignancies and cardiovascular diseases. CHIP has also been reporte...

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Bibliographic Details
Main Authors: Elisa Gelli, Claudia Martinuzzi, Debora Soncini, Concetta Conticello, Francesco Ladisa, Giulia Giorgetti, Dario Truffelli, Isabella Traverso, Francesco Lai, Fabio Guolo, Maurizio Miglino, Antonia Cagnetta, Antonella Laudisi, Sara Aquino, Daniele Derudas, Francesco Di Raimondo, Domenico A. Coviello, Roberto M. Lemoli, Michele Cea
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Multiple myeloma
Biomarkers
CHIP
Toxicity
Frailty
Online Access:https://doi.org/10.1038/s41598-024-79748-7

Internet

https://doi.org/10.1038/s41598-024-79748-7

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