The Cuprizone Mouse Model: A Comparative Study of Cuprizone Formulations from Different Manufacturers

The Cuprizone mouse model is widely used in studies on de- and remyelination. In the hands of different experimenters, the Cuprizone concentrations that lead to comparable levels of demyelination differ considerably. The reasons for this variability are unknown. In this study, we tested whether diff...

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Bibliographic Details
Main Authors: Malena Beecken, Louise Baumann, Elise Vankriekelsvenne, Katerina Manzhula, Theresa Greiner, Leo Heinig, Steffen Schauerte, Markus Kipp, Sarah Joost
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/13/10564