The proteomic and genomic teratogenicity elicited by valproic acid is preventable with resveratrol and α-tocopherol.

Previously, we reported that valproic acid (VPA), a common antiepileptic drug and a potent teratogenic, dowregulates RBP4 in chicken embryo model (CEM) when induced by VPA. Whether such teratogenicity is associated with more advanced proteomic and genomic alterations, we further performed this prese...

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Bibliographic Details
Main Authors: Yeh Chen, Ping-Xiao Lin, Chiu-Lan Hsieh, Chiung-Chi Peng, Robert Y Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4281235?pdf=render