Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities

Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities

Abstract Studies of radiation interaction with tumor cells often take apoptosis as the desired results. However, mitotic catastrophe and senescence are also promoted by clinically relevant doses of radiation. Furthermore, p53 is a well-known transcription factor that is closely associated with radio...

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Bibliographic Details
Main Authors: Ping Li, Xiongxiong Liu, Ting Zhao, Feifei Li, Qiqi Wang, Pengcheng Zhang, Ryoichi Hirayama, Weiqiang Chen, Xiaodong Jin, Xiaogang Zheng, Zhen Wang, Qiang Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00570-5

Internet

https://doi.org/10.1038/s41420-021-00570-5

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