Dicer regulates <it>Xist </it>promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a
<p>Abstract</p> <p>Background</p> <p>X chromosome inactivation is the mechanism used in mammals to achieve dosage compensation of X-linked genes in XX females relative to XY males. Chromosome silencing is triggered in <it>cis </it>by expression of the non-co...
| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
BMC
2008-10-01
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| Schriftenreihe: | Epigenetics & Chromatin |
| Online Zugang: | http://www.epigeneticsandchromatin.com/content/1/1/2 |