Differential effects of mitogen-activated protein kinase pathway inhibitors on P-glycoprotein activation
The aim of this study was to evaluate the effects of the mitogen-activated protein kinase (MAPK) pathway inhibitors SB203580, CMPD-1, SB239063, SP600125, and FR180204 on the activity of P-glycoprotein (P-gp) and to assess whether the MAPK pathway affects P-gp directly. Changes in the fluorescence of...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Association of Physical Chemists (IAPC)
2015-03-01
|
| Series: | ADMET and DMPK |
| Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/142 |