L-kynurenine induces NK cell loss in gastric cancer microenvironment via promoting ferroptosis

L-kynurenine induces NK cell loss in gastric cancer microenvironment via promoting ferroptosis

Abstract Background Natural killer (NK) cells play a major role in body’s fighting against various types of cancers. Their infiltration in the tumor microenvironment (TME) of gastric cancer (GC) are significantly decreased, which has been reported as a robust prognostic marker. However, the causes l...

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Váldodahkkit: Jian-Xin Cui, Xian-Hui Xu, Tao He, Jia-Jia Liu, Tian-Yu Xie, Wen Tian, Jun-Yan Liu
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: BMC 2023-03-01
Ráidu:Journal of Experimental & Clinical Cancer Research
Fáttát:
NK cell
Gastric cancer
Tumor microenvironment
L-kynurenine
Ferroptosis
Liŋkkat:https://doi.org/10.1186/s13046-023-02629-w

Interneahtta

https://doi.org/10.1186/s13046-023-02629-w

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