Impact of Sex Hormones on Macrophage Responses to Coxiella burnetii

Impact of Sex Hormones on Macrophage Responses to Coxiella burnetii

IntroductionQ fever, a zoonosis caused by Coxiella burnetii, affects more males than females despite a similar level of exposure. A protective role of estradiol has been reported in mice, suggesting that sex hormones are involved in C. burnetii infection. We wondered whether the responses of monocyt...

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Bibliographic Details
Main Authors: Laetitia Gay, Cléa Melenotte, Alexandre Lopez, Benoit Desnues, Didier Raoult, Marc Leone, Soraya Mezouar, Jean-Louis Mege
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
Coxiella burnetii
cytokines
inflammatory response
MDMs
sex hormones
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705088/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.705088/full

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