What Room for Two-Dimensional Gel-Based Proteomics in a Shotgun Proteomics World?

Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late 1980s. However, it is now often considered as an outdated technique for proteomics—a thing of the past. Although this opinion may be true for some biological questions, e.g., when analysis depth is of critica...

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Bibliographic Details
Main Authors: Katrin Marcus, Cécile Lelong, Thierry Rabilloud
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/8/3/17