(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hydroxy-17-[(R)-5-hydroxypentan-2-yl]-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}adamantane-1-carboxamide 0.25-hydrate

(1S,3R)-N-{(3S,10S,12S,13R,17R)-12-Hydroxy-17-[(R)-5-hydroxypentan-2-yl]-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}adamantane-1-carboxamide 0.25-hydrate

The title compound, C35H57NO3·0.25H2O, was synthesized from deoxycholic acid followed by a protection, a Mitsonobu substitution, a Staudinger reduction, formation of an amide and final reduction in the lateral chain. The compound crystallizes in the P1 space group with four steroid molecules and one...

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Bibliographic Details
Main Authors: Cristian Campos Fernandez, R. Procupez-Schtirbu, V. H. Soto-Tellini, J. C. Salazar, Vojtech Jancik
Format: Article
Language:English
Published: International Union of Crystallography 2022-10-01
Series:IUCrData
Subjects:
crystal structure
biological activity
bile salts
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2414314622009476

Internet

http://scripts.iucr.org/cgi-bin/paper?S2414314622009476

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