Analysis of the Targets and Glycosylation of Monoclonal IgAs From MGUS and Myeloma Patients

Analysis of the Targets and Glycosylation of Monoclonal IgAs From MGUS and Myeloma Patients

Previous studies showed that monoclonal immunoglobulins G (IgGs) of “monoclonal gammopathy of undetermined significance” (MGUS) and myeloma were hyposialylated, thus presumably pro-inflammatory, and for about half of patients, the target of the monoclonal IgG was either a virus—Epstein–Barr virus (E...

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Bibliographic Details
Main Authors: Adrien Bosseboeuf, Célia Seillier, Nicolas Mennesson, Sophie Allain-Maillet, Maeva Fourny, Anne Tallet, Eric Piver, Philippe Lehours, Francis Mégraud, Laureline Berthelot, Jean Harb, Edith Bigot-Corbel, Sylvie Hermouet
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
monoclonal immunoglobulin A (IgA)
multiple myeloma
monoclonal gammopathy of undetermined significance (MGUS)
infectious antigens
Epstein–Barr virus
hepatitis C virus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00854/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00854/full

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